Deoxymulundocandin--a new echinocandin type antifungal antibiotic.
نویسندگان
چکیده
A new echinocandin type antifungal antibiotic, deoxymulundocandin, C48H77N7O15, was isolated from the culture filtrate and mycelia of a fungal culture, Aspergillus sydowii (Bainier and Sartory) Thom and Church var. nov. mulundensis Roy (Culture No. Y-30462). The structure was established by comparative GC-MS analyses of the derivatized acid hydrolysates of deoxymulundocandin and mulundocandin as well as by the high field NMR experiments (COSY, NOESY and DEPT).
منابع مشابه
Mulundocandin, a new lipopeptide antibiotic. II. Structure elucidation.
The structure of a new antifungal antibiotic, mulundocandin, C48H77N7O16, was elucidated by high field NMR experiments e.g., homo- and heteronuclear correlation spectra, distortionless enhancement by polarization transfer (DEPT) spectra as well as nuclear Overhauser effect. The compound is a lipopeptide antibiotic belonging to the echinocandin class.
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ورودعنوان ژورنال:
- The Journal of antibiotics
دوره 45 5 شماره
صفحات -
تاریخ انتشار 1992